- Role of serum cortisol on children with asthma
This thesis presents studies with respect to the epidemiology of asthma in
children with and without nocturnal symptoms as well as its underlying
pathophysiology. Nocturnal respiratory symptoms are the clinical expression
of nocturnal airflow limitation and indicate a more severe disease state, also
named'nocturnal asthma'. Much research has been performed in the past
decades on the underlying mechanisms of nocturnal airflow limitation. This
thesis set out to contribute to a better insight into its pathophysiology by
investigating the role of serum cortisolevels.